ea0077ec1.1 | Early Career Prize Lecture Basic Science | SFEBES2021
De Franco Elisa
, Wakeling Matthew
, Owens Nick
, Johnson Matthew
, Flanagan Sarah
, Hattersley Andrew T
Understanding how pancreatic beta-cells develop during human development is essential to advance current protocols aimed at developing insulin-producing beta-cells in vitro and highlight therapeutic targets for diabetes treatment. Identifying the single-gene mutations which result in individuals developing diabetes in the first 6 months of life (a condition called neonatal diabetes) has the potential to give unique insights into the genes regulating human beta-cells w...